Service

Custom chemical synthesis

With our extensive experience in design and synthesis of ionizable lipids and other components of LNPs, UTgene offers tailored solutions to researchers and pharmaceutical companies in the field of drug delivery.

LNPs are widely used in the field of drug delivery, particularly for the delivery of nucleic acids such as mRNA, siRNA ,ASO and pDNA. Our expertise allows us to produce lipid molecules with specific properties, including different chain lengths, head groups, and functional groups. The customized synthesis of lipids enables researchers and pharmaceutical companies to obtain tailor-made lipid molecules that are crucial for the formulation and optimization of LNPs. These variations in lipid structure allow for the optimization of LNPs for specific applications, such as enhanced stability, improved drug loading capacity, or targeted delivery to specific cell types. Quality control measures are an essential part of the customized lipid synthesis process. Techniques such as nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and high-performance liquid chromatography (HPLC) are employed to assess the purity, structure of the synthesized lipids. These QC assures that the custom-synthesized lipids meet the required specifications for their intended use in LNP formulations.